Pharmaceutical compositions containing nifedipine and...

A - Human Necessities – 61 – K

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A61K 31/44 (2006.01) A61K 9/14 (2006.01) A61K 9/16 (2006.01)

Patent

CA 2126864

2126864 9313773 PCTABS00024 Compositions and processes for their preparation are provided in which nifedipine is coated onto a water soluble carrier in a mixture with polyvinylpyrrolidone or a copolymer of N-vinylpyrrolidone and vinyl acetate and a pharmaceutically acceptable acrylic based polymer. The ratio of the polyvinylpyrrolidone or N-vinylpyrrolidone/vinyl acetate copolymer to the content of nifedipine is in the range of from 1:1 to 1:10 and the ratio of the acrylic based polymer to the content of nifedipine is in the range of from 1:4 to 1:20. Compositions are provided which are suitable for once-a-day administration of nifedipine.

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