C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 503/10 (2006.01) A61K 31/424 (2006.01) A61P 31/04 (2006.01)
Patent
CA 2425314
An oxapenem compound which is, or is capable of forming, a zwitterion of formula Ia or Ib: (Ia), (Ib) wherein R is a C1-C8 branched or straight chain alkyl group which includes a protonated basic substituent. The compounds find particular use as high bioavailability .beta.-lactamase inhibitors.
L'invention concerne un composé oxapenem qui forme, ou peut former un zwitterion de formule Ia ou Ib: (Ia), (Ib) dans laquelle R représente un groupe alkyle en C¿1?-C¿8? ramifié ou linéaire qui comporte un substituant basique protoné. Ces composés ont un emploi particulier en tant qu'inhibiteurs à biodisponibilité élevée de .beta.-lactamase.
Pfaendler Hans Rudolf
Simpson Iain Nelson
Amura Limited
Ridout & Maybee Llp
LandOfFree
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