Pharmaceutical compositions containing polymer...

Details Pharmaceutical compositions containing polymer... Pharmaceutical compositions containing polymer...

A - Human Necessities

61

K

A61K 47/48 (2006.01) A61K 9/14 (2006.01) A61K 9/19 (2006.01) A61K 47/10 (2006.01) A61K 47/14 (2006.01) A61K 47/26 (2006.01)

Patent

CA 2105466

2105466 9313804 PCTABS00024 A lyophilized composition comprising (a) a conjugate comprising an N-alkyl methacrylamide-based copolymer and an anthracycline glycoside linked through a peptide spacer to the copolymer and (b) a cosolubilizing agent may optionally also contain (c) a filler. Also optionally, a targeting moiety may be linked to the copolymer of the conjugate via a peptide spacer. An injectable solution of the conjugate is obtained by reconstitution of the lyophilized composition.

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