Pharmaceutical compositions containing the long pentraxin ptx3

Details Pharmaceutical compositions containing the long pentraxin ptx3 Pharmaceutical compositions containing the long pentraxin ptx3

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C12N 15/10 (2006.01) C12N 15/86 (2006.01) C12P 21/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2315277

Pharmaceutical compositions are described containing a long pentraxin PTX3, particularly human PTX3, for the therapy of infectious and inflammatory or tumour diseases; expression vectors containing cDNA coding for PTX3; recombinant host cells transfected with such vectors; a method for producing substantial amounts of PTX3 involving the culturing of such cells, and the use of said vectors in the gene therapy of tumours.

Compositions pharmaceutiques contenant une pentraxine longue PTX3, en particulier, PTX3 humaine, servant à traiter des maladies infectieuses, inflammatoires ou tumorales; vecteurs d'expression contenant un ADNc codant pour PTX3; cellules hôtes de recombinaison transfectées par ces vecteurs; procédé servant à produire des quantités importantes de PTX3 et consistant à cultiver ces cellules et mise en application desdits vecteurs dans la thérapie génique de tumeurs.

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