Pharmaceutical compositions containing the phospholipase...

A - Human Necessities – 61 – K

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A61K 31/40 (2006.01) A61K 9/19 (2006.01) A61K 47/12 (2006.01) A61K 47/26 (2006.01)

Patent

CA 2322796

A lyophilized pharmaceutical composition is described which contains Sodium [[3- (2-amino- 1,2-dioxoethyl)- 2-ethyl-1-phenylmethyl)- 1H-indol-4- yl]oxy]acetate, a Solubilizer, and Stabilizer. Such compositions are storage stable and readily dissolve in aqueous medium to give injectable solution for treatment of sepsis, etc.

La présente invention concerne une composition pharmaceutique lyophilisée contenant un [[3-(2-amino-1,2-dioxoéthyl)-2-éthyl-1-phénylméthyl)-1H-indol-4-yl]oxy]acétate sodique, un solubilisant, et un stabilisant. Ces compositions, qui sont stables au stockage, donnent, après une dissolution facile dans un milieu aqueux, une solution injectable destinée notamment au traitement des septicémies.

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