Pharmaceutical compositions containing thiazolidinedione...

C - Chemistry – Metallurgy – 07 – D

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C07D 417/12 (2006.01) A61K 31/4427 (2006.01) A61K 31/4439 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2381976

A pharmaceutical composition which composition comprises an effective non- toxic amount of a compound of formula (I), or a tautomeric form thereof and/or a pharmaceutically acceptable salt thereof, and/or a pharmaceutically acceptable solvate thereof, wherein: A1 represents OH or -OSO2OH; R1 represents a hydrogen atom or a C1-6 alkyl group; and R2 and R3 each represent hydrogen or R2 and R3 together represent a bond; and a pharmaceutically acceptable carrier therefor; certain novel compounds used in such a composition and the use of such compounds and composition in medicine.

L'invention concerne une composition pharmaceutique comprenant une quantité efficace non toxique d'un composé représenté par la formule (I), ou d'une forme tautomère de celui-ci, et/ou d'un sel acceptable d'un point de vue pharmaceutique de celui-ci, et/ou d'un solvate acceptable d'un point de vue pharmaceutique de celui-ci, formule dans laquelle A?1¿ représente OH ou -OSO¿2?OH, R?1¿ représente un atome d'hydrogène ou un groupe alkyle C¿1-6?, et R?2¿ et R?3¿ représentent chacun l'hydrogène ou R?2¿ et R?3¿ représentent tous deux une liaison. L'invention concerne également un support acceptable d'un point de vue pharmaceutique. L'invention concerne enfin de nouveaux composés utilisés dans une telle composition, et l'utilisation de ces composés et de cette composition en médecine.

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