Pharmaceutical compositions containing tobramycin and...

Details Pharmaceutical compositions containing tobramycin and... Pharmaceutical compositions containing tobramycin and...

A - Human Necessities

61

K

A61K 31/70 (2006.01) A61K 9/00 (2006.01) A61K 47/36 (2006.01)

Patent

CA 2414737

Topically administrable aqueous solution compositions containing tobramycin and xanthan gum are disclosed. The solution compositions contain a buffering agent and a pH-adjusting agent in an amount sufficient to achieve a pH above 7.8 in order to minimize or avoid compatibility problems between tobramycin and xanthan gum.

Compositions sous forme de solutions aqueuses pour administration locale, qui contiennent un tampon et un agent de régulation du pH en quantité suffisante pour obtenir un pH supérieur à 7,8, ce qui permet de réduire à un minimum, voire d'éviter, les problèmes de compatibilité entre la tobramycine et la gomme de xanthane.

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