Pharmaceutical compositions containing triazole derivatives...

Details Pharmaceutical compositions containing triazole derivatives... Pharmaceutical compositions containing triazole derivatives...

A - Human Necessities

61

K

A61K 31/41 (2006.01) A61K 9/02 (2006.01) A61K 31/44 (2006.01)

Patent

CA 2080566

This invention relates to pharmaceutical compositions for rectal administration containing semi-synthetic glycerides produced by interesterification, and, as the active ingredient, triazole derivatives of the formula (see fig. I) wherein R1 is phenyl optionally sustituted with from one to three substituents independently selected from the group consisting of F, Cl, Br, I, CF3, (C1-C4)alkyl, (C1-C4)alkoxy, and 5-chloropyrid-2-yl; X is OH, F, Cl or Br; R2 is H2, CH3 or F; and R3 is H or F.

Compositions pharmaceutiques pour administration rectale; elles renferment des glycérides semi-synthétiques, produites par interestérification, et, comme ingrédients actifs, des dérivés du triazole de formule (voir fig. I), où R1 est un phényle avec substitution facultative par un ou trois substituants choisis indépendamment l'un de l'autre parmi F, Cl, Br, I, CF3, un groupe alkyle (C1-C4), alcoxy (C1-C4) et 5-chloropyrid-2-yle; X est OH, F, Cl ou Br; R2 est H2, CH3 ou F; et R3 est H ou F.

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