Pharmaceutical compositions containing urea

A - Human Necessities – 61 – K

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A61K 31/17 (2006.01) A61K 9/16 (2006.01) A61K 47/00 (2006.01) A61K 47/48 (2006.01)

Patent

CA 1114744

ABSTRACT Pharmaceutical compositions for application topically or by suppository comprise:- a) a medicament, preferably protected from de- gradation by moisture by being presented in small par- ticles of a waxy material, b) from 5% to 40% of an inclusion compound of urea with a straight-chain aliphatic compound, prefer- ably a fatty acid or alcohol, c) up to 50% of an inert insoluble powder such as starch, d) from 25% to 90% of an inert carrier, components a), b) and c) being dispersed in d). The compositions have good storage stability and a smooth texture.

329970

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