A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/425 (2006.01) A61K 9/00 (2006.01) A61K 31/427 (2006.01) A61K 47/02 (2006.01) A61K 47/10 (2006.01) A61K 47/12 (2006.01) A61K 47/44 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2434584
The invention relates to methods of increasing the bioavailability of orally administered epothilones. Epothilones administered by the methods of the invention are sufficiently bioavailable to have a pharmacological effect. The invention further relates to pharmaceutical compositions, pharmaceutical dosage forms, and kits for use in the methods of the invention.
L'invention concerne des procédés permettant d'augmenter la biodisponibilité d'épothilones administrées oralement. Les épothilones administrées selon les procédés présentés sont suffisamment biodisponibles pour avoir un effet pharmacologique. L'invention concerne en outre des compositions pharmaceutiques, des formes de dosages pharmaceutiques et des trousses à utiliser dans les procédés selon l'invention.
Bandyopadhyay Rebanta
Malloy Timothy M.
Panaggio Andrea
Raghavan Krishnaswamy
Varia Sailesh Amilal
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
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