Pharmaceutical compositions for mucolysis and treatment of...

A - Human Necessities – 61 – K

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A61K 31/685 (2006.01) A61K 31/661 (2006.01) A61P 11/00 (2006.01) A61P 11/06 (2006.01) A61P 29/00 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2314885

The use of phospholipids of formula (I) to reduce inflammation and the viscosity of mucus in a patient is described, wherein one of X, Y, or Z represents: (a) in which each R represents hydrogen or methyl, and each of the other two of X, Y, or Z represents -CO-R1 in which R1 represents linear or branched C11-21 alkyl or C11-21 alkenyl, unsubstituted or substituted with one or more substituents selected from the group consisting of halo, C1-6 linear or branched alkoxy or cyano.

L'invention concerne l'utilisation de phospholipides correspondant à la formule (I) pour réduire l'inflammation et la viscosité du mucus chez un patient. Dans ladite formule (I), un des symboles X, Y ou Z représente (a) où chaque R représente hydrogène ou méthyle et chacun des deux autres symboles parmi X, Y ou Z représente -CO-R?1¿ où R?1¿ représente un alkyle C¿11-21? ou un alcényle C¿11-21? linéaire ou ramifié, non substitué ou substitué avec un ou plusieurs substituants choisis dans le groupe constitué par halo, alcoxy C¿1-6? linéaire ou ramifié ou cyano.

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