Pharmaceutical compositions for poorly soluble drugs

Details Pharmaceutical compositions for poorly soluble drugs Pharmaceutical compositions for poorly soluble drugs

A - Human Necessities

61

K

A61K 9/14 (2006.01)

Patent

CA 2686756

The invention relates to solid dispersions of poorly soluble compounds formed by co-precipitation and hot melt extrusion, resulting in improved stability and bioavailability. The invention also relates to hot melt extrusion processes used to prepare such solid dispersions.

L'invention porte sur des dispersions solides de composés solubles de façon médiocre, formées par coprécipitation et extrusion à chaud, conduisant à une stabilité et une biodisponibilité accrues. L'invention porte également sur des procédés d'extrusion à chaud utilisés pour préparer des telles dispersions solides.

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