Pharmaceutical compositions for rectal and vaginal...

Details Pharmaceutical compositions for rectal and vaginal... Pharmaceutical compositions for rectal and vaginal...

A - Human Necessities

61

K

A61K 9/00 (2006.01) A61K 9/02 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01)

Patent

CA 2422424

The pharmaceutical compositions of the present invention comprise rectally and vaginally administerable dosage forms that contain effervescent agents as penetration enhancers for drugs. Effervescence occurs in the rectum or vagina, once the dosage form is administered or at a predetermined time following administration. The effervescent agents can be used alone or in combination with pH adjusting substance, which further promote dissolution and absorption of the active ingredient.

L'invention concerne des compositions pharmaceutiques comprenant des formes posologiques pouvant être administrées par voie rectale et vaginale, qui contiennent des agents effervescents comme activateurs de pénétration de médicaments. L'effervescence se produit dans le rectum ou le vagin après administration de la forme posologique ou au bout d'une durée prédéterminée consécutive à l'administration. Les agents effervescents peuvent être utilisés seuls ou en combinaison avec une matière de réglage de pH qui active davantage la dissolution et l'absorption de l'ingrédient actif.

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