Pharmaceutical compositions for sparingly soluble...

A - Human Necessities – 61 – K

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A61K 47/14 (2006.01) A61K 9/48 (2006.01)

Patent

CA 2166204

The invention relates to pharmaceutical compositions for sparingly soluble therapeutic agents as well as to a process for the preparation of such compositions. The solubiliser is polyglycerol fatty acid ester or sorbitan fatty acid ester in combination with lipophilic excipients and nonionic surfactants.

L'invention concerne des préparations pharmaceutiques pour principes actifs difficilement solubles, ainsi que des procédés permettant de produire ces préparations. On utilise comme agent de solubilisation des esters d'acide gras de polyglycérine ou des esters d'acide gras de sorbitanne, en combinaison avec des additifs lipophiles et des tensioactifs non ioniques.

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