Pharmaceutical compositions for the inhibition of tumor...

A - Human Necessities – 61 – K

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167/206, 167/283

A61K 31/045 (2006.01) A61K 31/66 (2006.01) A61K 31/74 (2006.01)

Patent

CA 1337176

Polyprenols and polyprenyl phosphates are of the formula Image wherein Image represents a trans-isoprene unit, Image represents a cis-isoprene unit, Image represents a dihydroisoprene unit, ? is an integer of 2 to 8, m is 0 or an integer of 5 to 18, n is 0 or 1, the sum of ? and m is in the range of 8 to 20, and X represents a hydrogen atom or -PO3MM' wherein M and M' may be the same or different and each is a hydrogen atom or a monovalent cation or both M and M' together form a divalent cation. They are useful as a medicament for the inhibition of tumor metastasis.

605469

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