Pharmaceutical compositions having a modified vehicle

Details Pharmaceutical compositions having a modified vehicle Pharmaceutical compositions having a modified vehicle

A - Human Necessities

61

K

A61K 47/44 (2006.01) A61K 31/545 (2006.01) A61K 47/14 (2006.01)

Patent

CA 2502025

A composition comprising: (a) one to three bioactive agents; and (b) a vehicle comprising; (i) a modified liquid carrier, and (ü) an un-modified liquid carrier wherein the ratio by volume of the modified liquid carrier to the un- modified liquid carrier is between 0.00001:99.99999 to less than 0.01:99.99, that provide the composition with predictable sustained-release properties and wherein immediately after manufacture of the composition, said composition can be administered to a host such that the one to three bioactive agents are released to the host on a sustained basis.

L'invention concerne une composition renfermant : (a) de un à trois agents bioactifs ; et (b) un excipient contenant (i) un support liquide modifié et (ii) un support liquide non modifié. Le rapport volumique du support liquide modifié et du support liquide non modifié est compris entre 0,00001:99,99999 et inférieur à 0,01:99,99. Ainsi, la composition fait preuve de propriétés prévisibles de libération prolongée et elle peut être, immédiatement après sa production, administrée à un hôte de manière que de un à trois agents bioactifs soient libérés vers l'hôte de manière prolongée.

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