C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 325/00 (2006.01) C07D 315/00 (2006.01) C07D 317/10 (2006.01) C07H 15/18 (2006.01) C07J 7/00 (2006.01) A61K 35/78 (1995.01)
Patent
CA 2283564
A pharmaceutical composition contains an extract obtainable from a plant of the genus Trichocaulon or Hoodia containing an appetite suppressant agent having the formula (1). A process for obtaining the extract and a process for synthesizing compound (1) and its analogues and derivatives is also provided. The invention also extends to the use of such extracts and compound (1) and its analogues for the manufacture of medicaments having appetite suppressant activity. The invention further provides novel intermediates for the synthesis of compound (1).
L'invention concerne une composition pharmaceutique contenant un extrait pouvant provenir d'une plante du genre Trichocaulon ou Hoodia qui contient un agent coupe-faim possédant la formule (1). L'invention concerne également un procédé d'obtention de l'extrait et un procédé de synthèse du composé (1) et de ses analogues et dérivés. L'invention concerne en outre l'utilisation de ces extraits et de ce composé (1) et de ses analogues dans la fabrication de médicaments dotés d'une activité coupe-faim. L'invention concerne enfin de nouveaux intermédiaires destinés à la synthèse du composé (1).
Horak Roelof Marthinus
Learmonth Robin Alec
Maharaj Vinesh
Van Heerden Fanie Retief
Vleggaar Robert
Csir
Smart & Biggar
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