Pharmaceutical compositions in form of nanoparticles...

A - Human Necessities – 61 – K

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A61K 9/51 (2006.01) A61K 31/12 (2006.01) A61K 38/23 (2006.01)

Patent

CA 2319565

Pharmaceutical compositions in form of nanoparticles comprising a composite material, consisting of at least one lipidic substance and of at least one amphiphilic substance, and of a pharmaceutically active principle. Said compositions, thanks to the surface and mass properties of said composite material, show an improvement in the incorporation of the active principles and an increase in the bioavailability of the poorly absorbable active principles.

L'invention porte sur des compositions pharmaceutiques se présentant sous forme de nanoparticules comprenant un matériau composite constitué d'au moins une substance lipidique et d'au moins une substance amphiphile, et d'un principe pharmaceutiquement actif. Ces compositions, grâce aux propriétés de surface et de masse du matériau composite, présentent une amélioration dans l'incorporation des principes actifs et un accroissement de la biodisponibilité des principes actifs à faible pouvoir d'absorption.

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