Pharmaceutical compositions in the form of stable sucralfate...

A - Human Necessities – 61 – K

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A61K 31/70 (2006.01) A61K 9/00 (2006.01) C07H 23/00 (2006.01)

Patent

CA 1306945

ABSTRACT Pharmaceutical compositions in the form of stable sucralfate suspen- sions free of suspending agents, wherein the sucralfate is present in the form of a gel having self-suspending properties and is suspen- ded in an aqueous carbohydrate solution in a quantity of between 1 and 40% of sucralfate by weight. Said gel has a surface area exceeding 200 m2/g and is prepared by dissolving powdered sucralfate in an HCl solution and then precipi- tating it with an NaOH solution added to a pH of between 4 and 4.5.

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