A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/235 (2006.01) A61K 9/08 (2006.01) A61K 47/02 (2006.01) A61K 47/18 (2006.01) A61K 47/26 (2006.01) A61K 47/34 (2006.01) A61P 31/04 (2006.01) A61P 31/10 (2006.01) A61P 31/12 (2006.01)
Patent
CA 2672538
Disclosed is a novel technique which enables to increase the anti-fungal, anti-viral or anti-bacterial activity of an alkyl gallate and enables to cause the alkyl gallate to be dissolved in water. Specifically disclosed is a pharmaceutical alkyl gallate composition which comprises: (A) an alkyl gallate which has an alkyl group having 5 to 16 carbon atoms; and (B) an alkyl gallate having an alkyl group in which the number of carbon atoms in the alkyl group is smaller than that of the alkyl gallate (A). Preferably, the number of carbon atoms in the alkyl group of the alkyl gallate (B) is 2 to 7. The composition may further comprise (C) at least one member selected from an alkali metal salt, boric acid, sodium borate and an organic salt.
L'invention concerne une nouvelle technique qui permet d'augmenter l'activité anti-fongique, anti-virale ou anti-bactérienne d'un gallate d'alkyle et permet d'amener le gallate d'alkyle à se dissoudre dans l'eau. L'invention concerne spécifiquement une composition pharmaceutique de gallate d'alkyle qui comprend : (A) un gallate d'alkyle qui a un groupe alkyle ayant 5 à 16 atomes de carbone ; et (B) un gallate d'alkyle ayant un groupe alkyle dans lequel le nombre d'atomes de carbone dans le groupe alkyle est inférieur à celui du gallate d'alkyle (A). De préférence, le nombre d'atomes de carbone dans le groupe alkyle du gallate d'alkyle (B) est de 2 à 7. La composition peut en outre comprendre (C) au moins un élément choisi dans le groupe constitué par un sel de métal alcalin, un acide borique, le borate de sodium et un sel organique.
Higuchi Masanori
Higuchi Tomihiko
Shibata Hirofumi
Kirby Eades Gale Baker
Microbiotech Inc.
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