Pharmaceutical compositions of amorphous atorvastatin and...

A - Human Necessities – 61 – K

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

A61K 9/16 (2006.01) A61K 9/14 (2006.01) A61K 31/40 (2006.01) A61P 3/06 (2006.01)

Patent

CA 2589537

Solid pharmaceutical compositions containing atorvastatin are disclosed. The compositions include a solid dispersion of amorphous atorvastatin and one or more optional pharmaceutically acceptable excipients. The solid dispersion is prepared by mixing crystalline atorvastatin with a melt-processible polymer and an optional stabilizer and an optional plasticizer at a temperature sufficiently high to soften or melt the polymer and to melt or dissolve the crystalline atorvastatin in the polymer, thereby forming a dispersion of amorphous atorvastatin.

L'invention concerne des compositions pharmaceutiques solides contenant une atorvastatine. Lesdites compositions comprennent une dispersion solide d'atorvastatine amorphe et un ou plusieurs excipient(s) éventuel(s) pharmaceutiquement acceptable(s). La dispersion solide est préparée par mélange d'une atorvastatine cristalline avec un polymère pouvant être traité par fusion, et éventuellement d'un stabilisateur et d'un plastifiant à une température suffisamment élevée pour ramollir ou faire fondre le polymère et pour faire fondre ou dissoudre l'atorvastatine cristalline dans ledit polymère, ce qui permet de former une dispersion d'atorvastatine amorphe.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Pharmaceutical compositions of amorphous atorvastatin and... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pharmaceutical compositions of amorphous atorvastatin and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pharmaceutical compositions of amorphous atorvastatin and... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1566341

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.