A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/10 (2006.01) A61K 47/34 (2006.01) A61K 47/38 (2006.01)
Patent
CA 2474838
A pharmaceutical composition comprises a solid amorphous dispersion comprising a low-solubility drug and a concentration-enhancing polymer and a lipophilic microphase-forming material. Alternatively, a solid amorphous dispersion comprising a low-solubility drug and a concentration-enhancing polymer is co- administered with a lipophilic microphase-forming material to an in vivo use environment.
L'invention concerne une composition pharmaceutique comprenant une dispersion amorphe solide renfermant un médicament à faible solubilité et un polymère renforçant la concentration, ainsi qu'un matériau formant des microphases lipophiles. Dans un autre mode de réalisation, une dispersion amorphe solide comprenant un médicament à faible solubilité et un polymère renforçant la concentration est administrée conjointement avec un matériau formant des microphases lipophiles dans un environnement d'utilisation <i>in vivo</i>.
Babcock Walter Christian
Friesen Dwayne Thomas
Perlman Michael Ellis
Rabenstein Mark David
Shanker Ravi Mysore
Pfizer Products Inc.
Smart & Biggar
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