Pharmaceutical compositions of dispersions of drugs and...

A - Human Necessities – 61 – K

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A61K 9/14 (2006.01) A61K 9/16 (2006.01)

Patent

CA 2450957

In one aspect, pharmaceutical compositions comprising dispersions of an acid- sensitive drug and a neutral dispersion polymer are disclosed. The acid- sensitive drug has improved chemical stability relative to dispersions of the drug and acidic polymers. In another aspect, pharmaceutical compositions of low solubility drugs and amphiphilic, hydroxy-functional vinyl copolymers are disclosed.

Dans un aspect, cette invention concerne des compositions pharmaceutiques comprenant des dispersions d'un médicament sensible à l'acide et d'un polymère de dispersion neutre. Ce médicament sensible à l'acide présente une stabilité chimique améliorée comparé aux dispersions composées du médicament et de polymères acides. Dans un autre aspect, cette invention concerne des compositions pharmaceutiques de médicaments peu solubles et de copolymères vinyliques amphiphiles à fonction hydroxy.

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