A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/18 (2006.01) A61K 38/16 (2006.01) A61K 47/10 (2006.01) A61K 47/18 (2006.01) A61K 47/02 (2006.01) A61K 47/12 (2006.01) A61K 47/26 (2006.01)
Patent
CA 2369444
The present invention provides aqueous pharmaceutical formulations of erythropoietin that are free of human serum blood products, stabilized with a quantity of an amino acid and a sorbitan mono-9- octadecenoate poly(oxy-1,2-ethanediyl) derivative. The present invention also provides aqueous stable, preserved pharmaceutical formulations of erythropoietin that contain an antimicrobial quantity of cresol and a quantity of an amino acid.
L'invention concerne des formulations pharmaceutiques aqueuses d'érythropoïétine, exemptes de produits sanguins du sérum humain et stabilisées par une quantité d'aminoacide et d'un dérivé de sorbitan mono-9-octadécénoate poly(oxy-1,2-éthanediyl). L'invention concerne également des formulations pharmaceutiques aqueuses d'érythropoïétine d'une stabilité permettant leur conservation, renfermant une quantité antimicrobienne de crésol et une quantité d'un aminoacide.
Begun Selima
Cheung Wing K.
Natarajan Jaya
Sanders Marilyn
Sharma Basant
Ortho-Mcneil Pharmaceutical Inc.
Smart & Biggar
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