Pharmaceutical compositions of hglp-1, exendin-4 and analogs...

A - Human Necessities – 61 – K

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A61K 38/26 (2006.01) A61K 38/16 (2006.01) A61K 47/02 (2006.01) A61K 47/48 (2006.01) A61P 3/00 (2006.01) A61P 3/10 (2006.01) A61P 5/48 (2006.01) C07K 14/575 (2006.01) C07K 14/605 (2006.01) C07K 17/00 (2006.01)

Patent

CA 2648440

The present invention is directed to pharmaceutical composition comprising a clear solution or an aqueous mixture, a suspension or a semisolid of at least one peptide compound selected from the group consisting of hGLP-1(7-36)-NH2 and analogs and derivatives thereof, hGLP-1(7-37)-OH and analogs and derivatives thereof and/or exendin-4 and analogs and derivatives thereof, zinc and solvent wherein at least 95% of the said peptide compound is dissolved by the solvent.

La présente invention concerne une composition pharmaceutique comprenant une solution limpide ou un mélange aqueux, une suspension ou un semi-solide d'au moins un composé peptidique choisi dans le groupe constitué par le hGLP-1(7-36)-NH2 et ses analogues et dérivés, le hGLP-1(7-37)-OH et ses analogues et dérivés et/ou l'exendine 4 et ses analogues et dérivés, de zinc et d'un solvant, au moins 95 % dudit composé peptidique étant dissous par le solvant.

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