Pharmaceutical compositions of muscarinic receptor antagonists

A - Human Necessities – 61 – K

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A61K 31/401 (2006.01) A61P 11/00 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2626612

Provided herein are pharmaceutical compositions comprising one or more muscarinic receptor antagonists ("MRA"), and at least one additional active ingredients selected from one or more ~2-agonists, p38 MAP kinase inhibitors, PDE-IV inhibitors, corticosteroids or a mixture thereof and optionally one or more pharmaceutically acceptable carriers, excipients or diluents. In addition, methods of treating autoimmune, inflammatory or allergic diseases or disorders are provided.

L'invention concerne des compositions pharmaceutiques comprenant un ou plusieurs antagonistes du récepteur muscarinique ("MRA") et au moins un principe actif supplémentaire sélectionné parmi un ou plusieurs éléments suivants : des ß2-agonistes, des inhibiteurs de la p38 MAP kinase, des inhibiteurs de PDE-IV, des corticostéroïdes ou un mélange de ceux-ci et éventuellement un ou plusieurs excipients ou diluants acceptables sur le plan pharmaceutique de ceux-ci. De plus, l'invention concerne des méthodes de traitement de maladies ou troubles auto-immuns, inflammatoires ou allergiques.

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