Pharmaceutical compositions of recombinant beta-interferon...

A - Human Necessities – 61 – K

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167/103.1

A61K 38/21 (2006.01) A61K 47/00 (2006.01) A61K 47/10 (2006.01) A61K 47/14 (2006.01) A61K 47/26 (2006.01)

Patent

CA 1294215

ABSTRACT OF THE DISCLOSURE Stable pharmaceutical compositions suitable for parenteral administration to animals or humans are prepared comprising a therapeutically effective amount of a recombinant IFN-.beta. protein dissolved in an inert carrier medium comprising as solubilizer/ stabilizer(s) one or more biocompatible non-ionic polymeric detergents or a combination of one or more biocompatible non-ionic polymeric detergents with an additional solubilizing and/or stabilizing agent, such as sodium dodecyl sulfate or glycerol. Said compositions are in liquid form or lyophflized.

549489

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