A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/20 (2006.01) A61K 31/4184 (2006.01)
Patent
CA 2623018
The present invention provides a pharmaceutical composition of telmisartan comprising a) a telmisartan compound, b) a surfactant, c) a basic agent, and d) at least one diluent wherein the composition comprises less than 25% of water soluble diluents. The telmisartan compound is preferably present from about 12.5% to about 15.5%. At least one water insoluble diluent is preferred for use in the pharmaceutical composition in an amount from about 40% to about 70% of the total weight of the pharmaceutical composition. A preferred water insoluble diluent is microcrystalline cellulose.
La présente invention concerne une composition pharmaceutique de telmisartan comprenant a) un composé de telmisartan, b) un tensioactif, c) un agent basique et d) au moins un diluant, la composition comprenant moins de 25 % de diluants solubles dans l~eau. Le composé de telmisartan est de préférence présent en une quantité comprise entre environ 12,5 % et environ 15,5 %. Il est préférable d~utiliser dans la composition pharmaceutique au moins un diluant insoluble dans l~eau en une quantité comprise entre environ 40 % et environ 70 % du poids total de la composition pharmaceutique. La cellulose microcristalline constitue un diluant insoluble dans l~eau préféré.
Kolatkar Gershon
Zisman Erela
Heenan Blaikie Llp
Teva Pharmaceutical Industries Ltd.
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