A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/52 (2006.01) A01N 43/90 (2006.01)
Patent
CA 2600046
The present invention relates to pharmaceutical compositions comprising as an active ingredient an isolated, chirally pure D-enantiomer of the quinazolinone derivative halofuginone having increased therapeutic activity and decreased side effects compared to the corresponding racemic mixtures, the composition being substantially free of the L-enantiomer and useful in the treatment of diseases and disorders associated with fibrotic conditions or cell proliferation.
La présente invention concerne une composition pharmaceutique comprenant comme principe actif un énantiomère D isolé de dérivé de quinazolinone halofuginone possédant une activité thérapeutique accrue et des effets secondaires moindres comparés aux mélanges racémiques correspondants, cette composition étant sensiblement exempte d'énantiomère L et convenant pour le traitement de maladies et de troubles associés aux états fibreux ou à la prolifération cellulaire.
Erez Mordechai
Halevi Karin
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Collgard Biopharmaceuticals Ltd.
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