Pharmaceutical compositions of the prodrug type, a process...

Details Pharmaceutical compositions of the prodrug type, a process... Pharmaceutical compositions of the prodrug type, a process...

A - Human Necessities

61

K

167/190, 167/195

A61K 31/185 (2006.01) A61K 31/43 (2006.01) A61K 31/575 (2006.01) C07C 51/567 (2006.01) C07C 53/128 (2006.01) C07C 57/30 (2006.01) C07C 62/06 (2006.01) C07D 499/00 (2006.01) C07D 519/00 (2006.01) C07J 9/00 (2006.01)

Patent

CA 1266828

Abstract: Pharmaceutical compositions of the prodrug type, a process for the preparation thereof, a process for the preparation of the as prodrug functioning compounds and compounds obtained herein. The pharmaceutical compositions of the invention contain organic acid anhydrides with formula 1 through 5, as well as the pharmacological acceptable salts thereof as prodrug functioning compounds, together with a suitable pharmaceutically acceptable gaseous, liquid or solid carrier. The prodrug systems of the invention possess as favourable property that they amend the residence time of the pharmaceutical composition in the body by influencing the transport system. Furthermore they increase the biological availabi- lity because of the more lipophilic properties of the anhy- dride compared with the acid, so that this improved admini- stration performance may contribute to lower dosages. Further the prodrug systems according to the in- vention contribute to the reduction of the complaints of patients, because the systems usually remove the unpleasant bitter taste and the flavour, whereas the gastro intestinal irritation of the organic acids is removed or reduced.

509171

Affiliated with

Also associated with

Rating

Pharmaceutical compositions of the prodrug type, a process... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pharmaceutical compositions of the prodrug type, a process..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pharmaceutical compositions of the prodrug type, a process... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1339466