A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/252
A61K 31/245 (2006.01) A61K 31/22 (2006.01)
Patent
CA 1166160
PHARMACEUTICAL COMPOSITIONS OF THERAPEUTIC VALUE IN THE TREATMENT OF ACUTE PULMONARY EDEMA, SOME SHOCK CONDITIONS AND HYPERFIBRINOLYSIS ABSTRACT OF THE DISCLOSURE Pharmaceutical compositions for use in the relief of acute pulmonary edema, different types of shock including anaphylactic shock, shock induced by bacterial endotoxins, and hyperfibrinolysis induced by substances which activate plasminogen, consist of solutions of an ester of L-arginine with an aliphatic alcohol in water at a pH between 5.5 and 8.5. The compositions may be provided in unit dosage form containing 0.25 - 100 mg of active substance per kilogram of body weight of the subject in need of treatment and are administered through the parenteral route. The esters may be provided in the form of a salt with a pharmaceutically acceptable organic or inorganic acid. The esters may be with methyl or ethyl alcohol. The compositions are more effective than acetylsalicylic acid and aprotinine.
366100
Baglioni Alessandro
Sportoletti Giancarlo
Italfarmaco S.p.a.
Kirby Eades Gale Baker
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