A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/00 (2006.01) A61K 9/06 (2006.01) A61K 31/00 (2006.01) A61K 47/14 (2006.01) A61K 47/32 (2006.01) A61K 47/34 (2006.01)
Patent
CA 2619715
The invention relates to the use of chemical fragrance ingredient to lower the melting point of active agents, thereby changing crystalline active agents into an amorphous state. The invention also relates to methods of enhancing the transdermal or transmucosal skin permeation or skin penetration of pharmacologically active agents to patients in need thereof. The compositions of the present invention present the additional benefits of being substantially alcohol-free and having a pleasant olfactory profile.
L'invention concerne l'utilisation d'un ingrédient de parfum chimique de manière à diminuer le point de fusion d'agents actifs, ce qui permet de changer des agents actifs cristallins en agents d'état amorphe. Cette invention a aussi pour objet des procédés d'amélioration de la perméation cutanée transdermale ou transmucosale ou la pénétration cutanée des agents actifs sur le plan pharmacologique, chez des patients le nécessitant. Lesdites compositions présentent les avantages supplémentaires d'être sensiblement exempts d'alcool et de posséder un profil olfactif plaisant.
Alberti Ingo
Besse Celine
Carrara Dario Norberto
Grenier Arnaud
Laetitia Henry
Alberti Ingo
Antares Pharma Ipl Ag
Besse Celine
Carrara Dario Norberto
Gowling Lafleur Henderson Llp
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