Pharmaceutical compositions with superior product...

Details Pharmaceutical compositions with superior product... Pharmaceutical compositions with superior product...

A - Human Necessities

61

K

A61K 9/20 (2006.01) A61K 31/513 (2006.01)

Patent

CA 2748895

The present invention provides novel formulations of isobutyric acid (2R,3R,4R,5R)-5-(4-amino -2-oxo-2H-pyrimidin-1-yl)-4-fluoro-2- isobutyryloxymethyl-4-methyl-tetrahydro-furan-3-yl ester) and hydroxypropylcellulose that provide high bulk density, low particle size better suited for improved compression and flow, good compression, and fast dissolution profiles.

La présente invention concerne de nouvelles formulations de l'ester (2R,3R,4R,5R)-5-(4-amino-2-oxo-2H-pyrimidin-1-yl)-4-fluoro-2-isobutyryloxyméthyl-4-méthyl-tétrahydro-furan-3-ylique de l'acide isobutyrique et de l'hydroxypropylcellulose, caractérisées par une masse volumique apparente élevée, par une faible taille des particules permettant une meilleure compression et une fluidité améliorée, par une bonne compression et par des profils de dissolution rapides.

Affiliated with

Also associated with

Rating

Pharmaceutical compositions with superior product... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pharmaceutical compositions with superior product..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pharmaceutical compositions with superior product... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1959150