Pharmaceutical compounds

Details Pharmaceutical compounds Pharmaceutical compounds

C - Chemistry, Metallurgy

07

C

C07C 235/66 (2006.01) A61K 31/165 (2006.01) A61K 31/33 (2006.01) C07C 237/48 (2006.01) C07C 323/38 (2006.01) C07C 323/42 (2006.01) C07D 209/48 (2006.01) C07D 211/88 (2006.01) C07D 275/04 (2006.01) C07D 295/13 (2006.01) C07D 309/06 (2006.01) C07D 335/02 (2006.01)

Patent

CA 2104626

ABSTRACT Pharmaceutical compounds of the formula: Image in which each R1 is hydrogen, C1-4 alkyl, C1-4 alkoxy, halogen or nitro, and n is 0, 1, 2 or 3, R2 is hydrogen, C1-4 alkyl or C2-4 alkenyl, R3 is hydrogen, C1-4 alkyl, C1-4 alkoxy, C1-4 alkylthio, halogen, nitro or -NR'R'' where R' and R'' are each hydrogen or C1-4 alkyl, R4 and R5 are each hydrogen, C1-4 alkyl, optionally substituted phenyl or C6-9 cycloalkyl optionally substituted by 1 to 4 C1-4 alkyl groups, R6 is optionally substituted phenyl, tetrahydronaphthyl, phthalimido, saccharinyl, glutaramido, C6-10 cycloalkyl optionally substituted with 1 to 4 C1-4 alkyl groups or a phenyl group, or C4-9 heterosubstituted cycloalkyl optionally substituted with 1-4 alkyl groups, x is 1, 2 or 3, y is 0 or 1 and z is 0, 1, 2 or 3; and salts thereof.

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