C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 409/14 (2006.01) A61K 31/4155 (2006.01) C07D 405/04 (2006.01) C07D 409/04 (2006.01)
Patent
CA 2507712
Pyrazole derivatives of the following formula (I), having affinity for the cannabinoidergic CB1 and/or CB2 receptors: (See formula I) wherein: - R is a group selected from: - C1-C10 alkyl; - aryl, arylalkyl or arylalkenyl, not substituted or having from one to four substituents, equal to or different from each other; - A is a group selected from the following: - an ether group of formula -(CH2)-O-(CH2)v-R" wherein - v is equal to 1 or 2; - R" is as defined in the present application; - a ketone group of formula -C(O)-Z', wherein Z' is as defined in the present application; - a substituent having an hydroxyl function of formula -CH(OH)-Z', Z' being as defined in the present application; - an amide substituent of formula -C(O)-NH-T', T' being as defined in the present application; - B is a group as defined in the present application; - D is an heteroaryl optionally substituted.
Lazzari Paolo
Murineddu Gabriele
Pinna Gerard Aime
Ruiu Stefania
Neuroscienze Pharmaness S.c. A. R.l.
Riches Mckenzie & Herbert Llp
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