Pharmaceutical delivery systems for hydrophobic drugs and...

Details Pharmaceutical delivery systems for hydrophobic drugs and... Pharmaceutical delivery systems for hydrophobic drugs and...

A - Human Necessities

61

K

A61K 31/573 (2006.01)

Patent

CA 2604943

A drug delivery system for oral administration of hydrophobic drugs with enhanced and extended absorption and improved pharmacokinetics is provided. In one embodiment, formulations comprising testosterone and testosterone esters, e.g., testosterone palmitate, are disclosed. Methods of treating a hormone deficiency or effecting male contraception with the inventive formulations are also provided.

La présente invention concerne un système d'apport de médicament destiné à l'administration par voie orale de médicaments hydrophobes avec une absorption améliorée et de plus longue durée ainsi qu'une meilleure pharmacocinétique. Dans une forme de réalisation, il s'agit de formulations comprenant de la testostérone et des esters de testostérone, par exemple du palmitate de testostérone. Cette invention se rapporte également à des méthodes de traitement d'une insuffisance hormonale ou de mise en oeuvre d'une contraception masculine au moyen des formulations selon l'invention.

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