Pharmaceutical dosage forms comprising a low-solubility drug...

A - Human Necessities – 61 – K

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Details

A61K 9/16 (2006.01) A61K 31/496 (2006.01) A61K 31/505 (2006.01) A61K 9/26 (2006.01)

Patent

CA 2577852

A dosage form comprises a low-solubility drug, and a precipitation-inhibiting polymer. The drug is in a solubility-improved form and in the form of particles at least partially coated with the precipitation-inhibiting polymer. Exemplified low-solubility drugs are ziprasidone and sildenafil. Exemplified precipitation-inhibiting polymer is HPMCAS.

La présente invention a trait à une posologie comportant un médicament à faible solubilité, et un polymère d'inhibition de précipitation. Le médicament est sous une forme à solubilité améliorée et sous la forme de particules enrobées au moins en partie avec le polymère d'inhibition de précipitation.

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