Pharmaceutical excipients comprising inorganic particles in...

A - Human Necessities – 61 – K

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A61K 9/14 (2006.01) A61K 9/16 (2006.01) C08J 3/215 (2006.01) C08L 5/00 (2006.01) C08L 5/02 (2006.01) A61K 9/20 (2006.01)

Patent

CA 2500923

A pharmaceutical excipient comprising a solid, reticulated matrix, wherein the matrix comprises an aggregation of inorganic particles in association with an organic polymeric material, defines a plurality of pores with a mean width in the range of about 0.01-500 m, and has a specific surface area of at least about 1 m2/g is described, as are products comprising such excipients, methods of making them and use thereof.

L'invention concerne un excipient pharmaceutique comprenant une matrice solide, réticulée, cette dernière comprenant une agrégation de particules inorganiques en association avec une matière polymère organique. Ledit excipient définit une pluralité de pores présentant une largeur moyenne comprise entre 0.01 et 500 ?m et présente une surface de contact spécifique d'au moins 1 m?2¿/g. L'invention concerne également des produits comprenant lesdits excipients, des procédés de fabrication de ces derniers ainsi que leur utilisation.

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