A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/519 (2006.01) A61K 45/06 (2006.01) A61P 9/08 (2006.01) A61P 15/10 (2006.01)
Patent
CA 2431147
The invention relates to a pharmaceutical formulation containing at least one compound of formula (I) wherein R1, R2, and X have the same meaning as cited in claim 1, and the physiologically acceptable salts thereof and/or solvates and a) at least one antithrombotic or b) at least one calcium antagonist or c) at least one prostaglandin or prostaglandin derivative for producing a medicament for treating angina, high blood pressure, pulmonary hypertension, congestive heart failure (CHF), chronic obstructive pulmonary disease (COPD), pulmonary heart disease, right ventricular failure, atheriosclerosis, permeability conditions of reduced cardiovascular patency, peripheral vascular illnesses, cerebral apoplexy, bronchitis, allergic asthma, chronic asthma, allergic rhinitis, glaucoma, irritable bowel syndrome, tumours, kidney failure, cirrhosis of the liver and for treating female sexual problems.
L'invention concerne une préparation pharmaceutique contenant au moins un composé de formule (I), dans laquelle R?1¿, R?2¿ et X ont la signification indiquée dans la revendication 1, ou ses sels ou solvates physiologiquement acceptables, ainsi que a) au moins un antithrombotique ou b) au moins un inhibiteur calcique ou c) au moins une prostaglandine ou un dérivé de prostaglandine, pour la production d'un médicament destiné à traiter l'angine de poitrine, l'hypertension artérielle, l'hypertension pulmonaire, l'insuffisance cardiaque congestive, la broncho-pneumopathie chronique obstructive (BPCO), le coeur pulmonaire, l'insuffisance cardiaque droite, l'athérosclérose, les conditions de perméabilité réduite des vaisseaux cardiaques, les maladies vasculaires périphériques, l'accident vasculaire cérébral, la bronchite, l'asthme allergique, l'asthme chronique, la rhinite allergique, le glaucome, le syndrome du côlon irritable, les tumeurs, l'insuffisance rénale, la cirrhose du foie, ainsi que les troubles sexuels féminins.
Eggenweiler Hans-Michael
Eiermann Volker
Fetherstonhaugh & Co.
Merck Patent Gesellschaft Mit Beschraenkter Haftung
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