Pharmaceutical formulation for intraveous or intramuscular...

A - Human Necessities – 61 – K

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A61K 38/31 (2006.01) A61K 47/12 (2006.01) A61K 47/18 (2006.01) A61K 38/12 (2006.01)

Patent

CA 2362772

A stable pharmaceutical formulation for intravenous or intramuscular administration of Octreotide, which is characterised in that the vehicle for injection of the peptide or pharmaceutically acceptable salts thereof contains glycine in concentrations ranging from 10 to 60 mM and aqueous solution of hydrochloric acid in sufficient quantity to adjust the pH of the formulation to values between 3.0 and 4.2.

L'invention concerne une formulation pharmaceutique stable pour l'administration par voie intraveineuse ou intramusculaire d'Octréotide dont le support d'injection du peptide ou de ses sels pharmaceutiquement acceptables contient de la glycine en proportion allant de 10 mM à 60 mM et une solution aqueuse d'acide chlorhydrique en quantité suffisante pour régler le pH de la formulation à des valeurs comprises entre 3,0 et 4,2.

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