Pharmaceutical formulation for reducing pulmonary blood...

A - Human Necessities – 61 – K

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A61K 9/20 (2006.01) A61K 31/505 (2006.01)

Patent

CA 2733651

The invention relates to pharmaceutical formulations for lowering pulmonary blood pressure, comprising microni-zed ambrisentan, preferably in the form of an intermediate, together with a hydrophilicizing agent. The invention further provides methods of producing pharmaceutical formulations comprising micronized ambrisentan.

Linvention concerne des formulations pharmaceutiques pour la réduction de la pression artérielle pulmonaire, qui contiennent de lAmbrisentan micronisé, de préférence sous la forme dun intermédiaire, accompagné dun agent dhydrophylisation. Linvention concerne également des procédés de fabrication de formulations pharmaceutiques, qui contiennent de lAmbrisentan micronisé.

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