Pharmaceutical formulation for the production of rapidly...

A - Human Necessities – 61 – K

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A61K 9/00 (2006.01) A61K 9/20 (2006.01) A61K 9/16 (2006.01)

Patent

CA 2688389

The invention relates to a pharmaceutical formulation in the form of compacts containing a) 60 - 97 % by weight of sugar or sugar alcohols, b) 1 - 25 % by weight of a disintegration agent selected from the group consisting of croscarmellose, sodium carboxymethyl starch and L-hydroxypropyl cellulose, c) 1 - 15 % by weight of water insoluble film-forming polymers, d) 0 - 15 % by weight of water-soluble polymers, and e) 0 - 15 % by weight of additional conventional pharmaceutical adjuvants, the sum of the components a) to e) totalling 100 % by weight.

La présente invention concerne une préparation pharmaceutique se présentant sous forme de produits agglomérés contenant a) 60 - 97 % en poids de sucre ou d'alcools de sucre, b) 1 -25 % en poids d'un agent de délitement choisi dans le groupe formé par la croscarmellose, le carboxyméthylamidon sodique et la L-hydroxypropylcellulose, c) 1 - 15 % en poids de polymères insolubles dans l'eau et filmogènes, d) 0 - 15 % en poids de polymères hydrosolubles, et e) 0 - 15 % en poids d'autres adjuvants pharmaceutiques courants, la somme des composants a) à e) s'élevant à 100%.

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