Pharmaceutical formulation for treating the upper digestive...

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/46 (2006.01) A61K 31/58 (2006.01)

Patent

CA 2731312

The invention relates to an effervescent tablet for preparing a mouth rinsing solution, wherein the effervescent tablet exhibits a high release rate of budesonide A high availability of the active ingredient during use as a mouth rinsing solution on the inflamed mucosa of the upper digestive tract is thereby achieved. The advantage of the formulation according to the invention lies in the bioavailability comparable to oral forms of administration, which allows the formulation to be used safely over an extended period of time.

L'invention concerne un comprimé effervescent pour la préparation d'une solution de bain de bouche, le comprimé effervescent présentant une grande vitesse de libération de budésonide. De ce fait, on obtient une disponibilité élevée du principe actif lors de l'utilisation en bain de bouche sur les muqueuses enflammées du tractus digestif supérieur. L'avantage de la formulation selon l'invention réside dans la biodisponibilité comparable à celle de formes d'administration orales, ce qui permet une utilisation sûre sur une période prolongée.

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