Pharmaceutical formulation of iressa comprising a...

A - Human Necessities – 61 – K

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A61K 47/38 (2006.01) A61K 9/28 (2006.01) A61K 31/517 (2006.01) A61K 31/5377 (2006.01) C07D 239/94 (2006.01)

Patent

CA 2476587

A pharmaceutical composition comprising 4-(3'-chloro-4'-fluoroanilino)-7- methoxy-6-(3-morpholinopropoxy)quinazoline or a pharmaceutically acceptable salt thereof (the Agent) and a water-soluble cellulose ether or an ester of a water-soluble cellulose ether. The water-soluble cellulose ether or ester of a water-soluble cellulose ether present in the composition inhibits the rate of precipitation of the Agent from solution.

L'invention concerne une composition pharmaceutique comprenant de la 4-(3'-chloro-4'-fluoroanilino)-7-méthoxy-6-(3 morpholinopropoxy)quinazoline ou un de ses sels pharmaceutiquement acceptables de celle-ci (l'Agent) ainsi qu'un éther de cellulose soluble dans l'eau ou un ester d'un éther de cellulose soluble dans l'eau. Ledit éther de cellulose soluble dans l'eau ou l'ester d'un éther de cellulose soluble dans l'eau, présent dans ladite composition, inhibe le taux de précipitation de l'Agent de la solution.

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