Pharmaceutical formulations

A - Human Necessities – 61 – K

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A61K 9/30 (2006.01) A61K 9/16 (2006.01)

Patent

CA 1302259

ABSTRACT Pharmaceutical Formulation The residence time in the human stomach of pharmaceutical, gastric controlled release, solid units can be increased significantly if the units have a density that is much higher than normal. A preferred oral dosage form according to the invention comprises a capsule or other dosage form having a dimension above 2mm and that contains one or more of the said units. The density of each unit is preferably at least 2.5 and usually at least 2.7g/ml and can conveniently be achieved by including at least 50% by weight of a weighting agent such as barium sulphate.

546905

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