Pharmaceutical formulations and methods of use

A - Human Necessities – 61 – K

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Details

A61K 9/36 (2006.01) A61K 9/22 (2006.01) A61K 31/195 (2006.01)

Patent

CA 2595470

This invention relates to new pharmaceutical formulations, and to new medical uses, of gabapentin and pregabalin. The formulations may comprise up to three components including an immediate release component, a sustained release component and a delayed release component. The proportion of each component in the formulation may be adjusted to achieve the desired AUC and therapeutic effect following oral administration in a human subject.

La présente invention concerne de nouvelles préparations pharmaceutiques et de nouvelles utilisations médicales de gabapentine et de pregabaline. Ces préparations peuvent comprendre jusqu'à trois composants comprenant un composant à libération immédiate, un composant à libération soutenue et un composant à libération retardée. La proportion de chaque composant dans cette préparation peut-être réglée de façon à obtenir l'AUC souhaité et l'effet thérapeutique suivant l'administration à une personne par voie orale.

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