Pharmaceutical formulations and use thereof in the...

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/55 (2006.01) A61K 31/00 (2006.01) A61K 31/357 (2006.01) A61K 31/401 (2006.01) A61K 31/4025 (2006.01) A61K 31/403 (2006.01) A61K 31/404 (2006.01) A61K 31/4166 (2006.01) A61K 31/4184 (2006.01) A61K 31/435 (2006.01) A61K 31/497 (2006.01) A61K 31/55 (2006.01) A61K 31/551 (2006.01) A61K 31/554 (2006.01) A61P 3/10 (2006.01) A61P 9/04 (2006.01) A61P 9/10 (2006.01)

Patent

CA 2382387

The present invention relates to use of an inhibitor of the renin-angiotensin system (RAS) or a pharmaceutically acceptable derivative thereof, particularly ramipril or ramiprilat, in the manufacture of a medicament for the prevention of stroke, diabetes and/or congestive heart failure (CHF). The present invention further relates to a method of prevention and/or treatment of stroke, diabetes and/or CHF, comprising administering a therapeutically effective amount of an inhibitor of the RAS or a pharmaceutically acceptable derivative thereof, particularly ramipril or ramiprilat, to a patient in need of such prevention and/or treatment.

La présente invention concerne l'utilisation d'un inhibiteur du système rénine-angiotensine (SRA) ou d'un dérivé pharmaceutiquement acceptable de ce dernier, plus particulièrement le ramipril ou le ramiprilat, dans la préparation d'un médicament destiné à prévenir l'accident cérébrovasculaire, le diabète et/ou l'insuffisance cardiaque globale. La présente invention concerne également un procédé de prévention de l'accident cérébrovasculaire, du diabète et/ou de l'insuffisance cardiaque globale qui consiste à administrer une quantité thérapeutiquement efficace d'un inhibiteur de SRA ou d'un dérivé pharmaceutiquement acceptable de ce dernier, plus particulièrement du ramipril ou du ramiprilat, à un patient pour qui la prévention et/ou le traitement de ce type est/sont nécessaires.

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