Pharmaceutical formulations comprising clopidogrel

A - Human Necessities – 61 – K

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A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 31/60 (2006.01)

Patent

CA 2663311

Melt granulate in the form of a solid state dispersion of the drug in a pharmaceutically acceptable carrier, wherein said melt granulate comprises a pharmaceutically active compound, preferably clopidogrel, at least one carrier material, and optionally pharmaceutically acceptable excipients and method of making said melt granulate.

L'invention concerne un granulé fondu sous la forme d'une dispersion à l'état solide du médicament dans un support acceptable du point de vue pharmaceutique, ledit granulé fondu comprenant un composé pharmaceutique actif, de préférence le clopidogrel, au moins une matière de support et, facultativement, des excipients acceptables du point de vue pharmaceutique. L'invention concerne aussi un procédé de fabrication dudit granulé fondu.

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