Pharmaceutical formulations comprising indolinone derivatives

Details Pharmaceutical formulations comprising indolinone derivatives Pharmaceutical formulations comprising indolinone derivatives

A - Human Necessities

61

K

A61K 31/40 (2006.01) A61K 31/675 (2006.01)

Patent

CA 2466807

The present invention is directed to formulations comprising 3-(pyrrol-2- ylmethylidene)-2-indolinone derivatives that modulate the activity of protein kinases ("PKs"). Methods of treating diseases related to abnormal PK activity utilizing the formulations comprising these compounds and methods of making these formulations are also disclosed.

Cette invention concerne des préparations renfermant des dérivés de 3-(pyrrol-2-ylméthylidène)-2-indolinone qui modulent l'activité des protéines kinases (PK). Cette invention concerne également des méthodes de traitement de maladies associées à une activité anormale des protéines kinases faisant intervenir ces préparations renfermant ces composés ainsi que des méthodes de fabrication de ces préparations.

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