C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 335/20 (2006.01) A61K 31/185 (2006.01) A61K 31/655 (2006.01) A61K 31/66 (2006.01) A61K 31/795 (2006.01) A61K 49/00 (2006.01) C07C 335/16 (2006.01) C07F 9/12 (2006.01) C07F 9/38 (2006.01)
Patent
CA 2179988
The oligomers of the present invention are polythioureas having 3 to 50 recurring units derived from aromatic diamines substituted with anionic groups, and having a number average molecular weight of less than 10,000. These oligomers are water-soluble, preferably have a rigid backbone, and are pharmaceutically acceptable. The oligomers are useful for the treatment and/or diagnosis of AIDS.
Les oligomères de la présente invention sont des polythiourées comportant de 3 à 50 unités récurantes dérivées de diamines aromatiques substituées par des groupes anioniques. Ces oligomères, caractérisés par un poids moléculaire moyen inférieur à 10.000, sont hydrosolubles, comportent de préférence un squelette rigide et sont pharmaceutiquement acceptables. Ces oligomères conviennent particulièrement au traitement et/ou au diagnostic du SIDA.
Cardin Alan D.
Fordyce William A.
Kruper William J.
Mullins Michael J.
Peet Norton P.
Merrell Pharmaceuticals Inc.
Osler Hoskin & Harcourt Llp
The Dow Chemical Company
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